ClindaHEXAL 150 / 300

In Drug by Astrid Delannoy Views: 353

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Areas of application

All fields of application by the manufacturer

Following, the 150 / 300 in conjunction with ClindaHEXAL applications, there are more detailed information:

• Inflammation
• Inflammation of the mouth and throat area
• Pneumonia
• Skin infections
• Infections due to streptococci
• Tonsillitis
• Runny nose, sinus infection

Drug overview

ClindaHEXAL 150 / 300 is available in following variants:
(Please note also our notes about the price and payment information)

Variant comparison
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Pack size and dosage form	Potency (dosage per capsule)	Cheapest price per Pack (with surcharge),(Versandkosten)
12 Capsules	150 Mg clindamycin	12,96 EUR alternatives
30 Capsules	150 Mg clindamycin	19,21 EUR alternatives
60 Capsules	150 Mg clindamycin	46.13 EUR alternatives
12 Capsules	300 Mg clindamycin	14,33 EUR alternatives
30 Capsules	300 Mg clindamycin	23.17 EUR alternatives
60 Capsules	300 Mg clindamycin	39,81 EUR alternatives
6 of 6 drugs

The following table shows drugs containing the same active ingredient (clindamycin) such as ClindaHEXAL 150 / 300:
(Please note also our notes about the price and payment information)

Sort according to: drug dosage form
Drug	Pharmaceutical form
Clinda saar 150 mg / 300 mg / 600 mg film-coated tablets	Film-coated tablet
Basocin Acne gel	Gel
Clindastad 150 mg / – 300 mg	Hard capsule
Clin Sanorania 150 mg / – 300 mg	Capsule
Sandoz clindamycin 300 mg hard capsules	Capsule
displaying 5 of 11 drugs complete table

• All existing medicines containing the same active ingredient as ClindaHEXAL 150 / 300

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Other components

The following substance not effective components are part of the drug:

• Lactose 1H2O
• Corn starch
• Dye E-171
• Gelatine
• Magnesium stearate
• Talcum powder

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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How ClindaHEXAL works 150 / 300

ClindaHEXAL 150/300 contains the active ingredient clindamycin. Learn more about the applications and the action of clindamycin below. Read also the information about the Lincosamides, among which the active ingredient clindamycin drug group. Please note the special effect of ClindaHEXAL 150 / 300 is also

Fields of application of the active substance: clindamycin

Clindamycin is a drug for treating acute and chronic infections that are caused by pathogens such as bacteria, Spore formers and cell parasites. Inside the body, clindamycin is at:

• Knochenentzündungen and joint infections
• bacterial-related acute bronchitis and pneumonia
• Infections of the throat-nose ears range
• Tooth and jaw infection
• Infections of the pelvic or abdominal area
• Infections of the skin, inflammation of the soft tissues (tendons, muscles and ligaments)
• Infections of the female genital organs
• Septicemia
• Scarlet fever.

Clindamycin can be also externally applied on the skin. So soothes and heals it locally, for example, acne and other skin infections. Still, the active substance can be used also to the prevention of infections in surgical procedures. The risk, for example, of a Herzinnenhautentzündung is decreased for patients with increased risk of infection. Patients who are allergic to antibiotics from the Group of Penicillins or the cephalosporins, clindamycin can use as a replacement.

In-depth information is available to the following fields of application of clindamycin:

• Acne
• Inflammation
• Inflammation of the mouth and throat area
• Pneumonia
• Skin infections
• Infections due to streptococci
• Tonsillitis
• Runny nose, sinus infection
• Urinary tract infections
• chronic bronchitis
• Osteomyelitis

Mode of action of clindamycin

Clindamycin is an antibiotic of the subgroup of the Lincosamides. The active ingredient in many forms can be given due to its chemical structure. The types of applications include the external application on the skin or the mucous membrane of the pubic area, the internal use to swallow or the Administration as an infusion into the blood stream.

A special feature of Clindamycins is its ability to penetrate the body tissues. High effect concentrations can be achieved even in bone and synovial fluid. Clindamycin penetrates but poorly into the brain fluid. Infections such as for example meningitis (meningitis) can be treated with the active substance therefore not reliable.

Clindamycin is stronger against bacteria effectively than lincomycin, which also belongs to the drug group of the Lincosamides.

Special features of the effect of ClindaHEXAL 150/300

ClindaHEXAL 150 capsule contains 174,2 mg clindamycin HCl 1H2O. This is equivalent to 150 mg clindamycin. A capsule of ClindaHEXAL 300 contains 348.4 mg clindamycin HCl 1H2O. This is equivalent to 300 mg clindamycin.

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Warnings & precautions

• A treatment with the drug takes more than three weeks, regularly to monitor the liver, kidney, and blood values, as well as the functioning of the kidneys by the doctor.
• Severe and persistent diarrhea during treatment can be a life-threatening condition (pseudomembranous enterocolitis). A doctor must be searched on, immediately.
• Is an acne is treated with the drug, the skin four weeks should improve. A long-term use is not recommended.
• The drug must be applied not locally on the eye.
• The drug is not to treat of the meningitis (meningitis). The concentrations achieved in brain fluid are too small to do so.

Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.

Should you perceive the signs of an allergic reaction, immediately inform a doctor.

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Interactions

What interactions of active substance of clindamycin in ClindaHEXAL 150/300 are known? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

Clindamycin and macrolide antibiotics (such as erythromycin, clarithromycin, Roxithromycin, azithromycin) weaken off each other in their effect.

If muscle relaxants (such as baclofen, Tizanidine, Tolperisone) or anaesthetic gases (such as diethyl ether, nitrous oxide, halothane, enflurane, isoflurane, desflurane, sevoflurane) along with clindamycin are used, there may be a stronger muscle attenuating effect.

Clindamycin administered as solution in the blood stream (such as infusion), so it must be mixed in no case with aminophylline (for bronchial extension), ampicillin (wide band penicillin), Calciumgluconat (calcium substitution), magnesium sulfate (magnesium substitution), phenytoin sodium (disambiguation) or active substances from the Group of the barbiturates (sedatives), such as Methohexital, Thiopental, and phenobarbital.

Through a modified intestinal flora during a Clindamycinbehandlung pregnancy prevention drugs (“pill”) can become worse. Therefore, in addition to mechanical pregnancy prevention measures (condoms) are to apply.

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Dosage

The capsules should be taken whole, upright upper body and with a large glass of water. This prevents application failures and possible irritation of the esophagus. Taking can independently of meals.

Adults and adolescents over 14 years of age take 600 to 1800 milligrams of clindamycin a day depending on the location and severity of the infection. This dose is distributed on three or four individual income.

Children between four weeks and 14 years of age occupy eight to 25 mg clindamycin per kilogram of body weight per day depending on the location and severity of the infection. The daily intake is better to three divided four individual income.

Clindamycin used for Chlamydia infections or in infections in the small pelvis, so the duration of treatment should be 10 to 14 days.

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Contra-indications

The following information on contra-indications for the purposes of ClindaHEXAL 150 / 300 in General, pregnancy & lactation, and in children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

When ClindaHEXAL 150 / 300 not used?

Clindamycin may be applied not in hypersensitivity or allergy against this active substance or a different way from the Group of the Lincosamides. Here is the risk of a life-threatening allergic shock. Only under careful medical supervision and risk benefit clindamycin may

• placed internally (via the gastro intestinal tract, vein or muscle) with reduced functioning of the liver in acute or chronic intestinal diseases with abnormal muscle weakness (myasthenia gravis) and in Parkinson’s disease
• applied externally to the skin, but also in the vagina colitis or inflammation of the mucous membrane are in bowel diseases such as Crohn’s disease, ulcerative by small and large intestine.

An allergy to Penicillins, there is a concurrent allergic to clindamycin is possible. Even with only General allergy tilt the doctor must carefully consider against each other risks and benefits of therapy with the active substance. Clindamycin is not for infections with clindamycin insensitive pathogens (such as yeast and Trichomonads = men) given. Clindamycin may be administered only diluted into the vein. Otherwise it could lead to intolerance reactions such as nausea, feeling of heat or rarely even to dangerous heart and cardiovascular complaints (for example, the drop in blood pressure or the cardiac arrest).

What must you consider when pregnancy and breast-feeding?

The safety of clindamycin in pregnancy is not sufficiently proven. Therefore benefit and risk of an application carefully from the attending physician must be weighed against each other.

No local application in the vagina may be in pregnant women with an increased risk of complications, as well as visceral placenta partially or completely covered the inner cervix, or detachment of Mutterkuchens.

In the first third of the pregnancy, the application in the vagina may be generally only after careful medical assessment of risks and benefits.

Clindamycin is transferred through breast milk to the baby. When the baby there may then be diarrhea, fungal besiedelungen on the mucous membranes or the emergence of an allergy. Before starting treatment, the mother should breastfeed off so just in case.

What is taken into account in children?

Infants from four weeks and young children can get drugs with active ingredient clindamycin. The dose is individually by age and body weight of the attending physician.

Manufacturer: HEXAL AG
Active ingredient: Clindamycin

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Side effects

What side effects can the active ingredient clindamycin, ClindaHEXAL 150 / 300 have? Below, you will learn the most important thing possible, well-known side effects of clindamycin in ClindaHEXAL 150/300. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).

Common side effects: when systemic application: digestive disorders such as abdominal pain, diarrhea, nausea, vomiting.

Where in the vagina: Cervical infections, vaginal mucous membrane infections.

Uncommon side effects: when systemic application: temporary liver enzyme increase.

The dose in the muscle: Local irritation, local pain, local hardening, local sterile abscesses.

The dose in the vein: Pain, phlebitis.

Where in the vagina: Outer genital irritation.

Rare side effects: when systemic application: allergies (masern-like redness), swelling of the skin, ankle swelling, drug fever, again forming back blood reduction, muscle weakness, itching, vaginal discharge, multiform, exuding redness, scaly skin inflammations, Lyell Syndrome (blistering and skin separation of similar to verbrühter skin).

When applied to the skin: Headache, sore throat, dry skin, frequent urination, allergic reaction.

Where in the vagina: Skin rash (eczema), urticaria.

Very rare side effects and individual cases: when systemic application: life-threatening allergic shock, temporary inflammation of the liver (with yellow skin color), Polyarthritis (arthritis), pseudomembranous Enterocolitis (severe intestinal inflammation of the small and large intestine).

Where in the vagina: Gastrointestinal disorders such as heartburn, nausea, abdominal pain, diarrhea, constipation, dizziness, headaches, temporary increase of the liver enzyme values, allergies (masern-like redness), swelling of the skin, ankle swelling, drug fever, again forming back blood reduction, muscle weakness, itching, vaginal discharge, multiform, exuding redness, scaly skin inflammations, Lyell Syndrome (blistering and skin separation of similar to verbrühter skin).

Side effects without specifying the frequency: when systemic application: inflammation of the mucous membrane of the mouth, inflammation of the throat.

Where in the vagina: Yeast propagation, Trichomonadenvermehrung.