Amitriptyline beta 10

In Drug by Serge Ledoux Views: 7

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Area of application

Application area called by the manufacturer

To this, the beta 10 in combination with amitriptyline application area there is in-depth information:

• Depression

Variant comparison

In the following variants amitriptyline is available as beta 10:
(Please note also our notes about the price and payment information)

Variant comparison
-Ad-
Pack size and dosage form	Potency (dosage per film-coated tablet)	Cheapest price per Pack (with surcharge),(Versandkosten)
100 Film-coated tablets	10 Mg amitriptyline	12.32 EUR (5.00 EUR), price (3,95 EUR shipping) price comparison
50 Film-coated tablets	10 Mg amitriptyline	11.10 EUR (5.00 EUR), price (3,95 EUR shipping) price comparison
20 Film-coated tablets	10 Mg amitriptyline	Price 10,29 EUR (5.00 EUR), (3,95 EUR shipping) price comparison

• Similar drugs

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Other components

The following substance not effective components are part of the drug:

• Hypromellose
• Indigocarmin (E 132)
• Aluminium hydroxide
• Calcium hydrogen phosphate dihydrate
• Carboxymethylstärke sodium (type A)
• high colloidal silicon dioxide
• Lactosemonohydrat
• MACROGOL 4000
• Magnesium stearate
• Corn starch
• Titanium dioxide (E 171)

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Amitriptyline appears beta 10

Amitriptyline beta 10 contains the active ingredient amitriptyline. Learn more about the applications and the action of amitriptyline below. Read also the information about the drug group approached and tetrazyklische antidepressants, among which the active ingredient amitriptyline. Please note the special effect of amitriptyline is also beta 10

Fields of application of the active substance: amitriptyline

Amitriptyline is prescribed for the treatment of depressive disorders (depression). Specifically, the active ingredient helps mental complaints where a bad mood or anxiety in the foreground are. It includes also anxiety disorders, which also adversely affect the mood. Because of the calming effect helps amitriptyline also against the disease-related sleep disorders and should be taken in the evening.

The active ingredient can be applied also for chronic pain who have often a psychological component, within a therapy concept. The pain scale that covers amitriptyline here, ranging from mild to moderately severe pain to point to strong to very strong pain. For example, headache migraine can be treated with amitriptyline-Anfällen and fibromyalgia (pain in the musculoskeletal system).

In-depth information is available to the following application areas of amitriptyline:

• Depression
• Pain (strong to very strong)
• Anxiety disorders

Effect of amitriptyline

Amitriptyline belongs to the tricyclic antidepressants drug group and has their mode of action.

All of the brain’s nerve reactions are mediated by Messenger substances such as serotonin and norepinephrine. These messengers are stored in small vesicles in the nerve endings and are awarded for excitation of nerve. So they get to other nerves and bind there on special binding sites from (receptors). As a result, the affected nerves forward the stimulus signal. After they have fulfilled their task so, be the messengers of special transport systems again in their store recorded or degraded by enzymes.

Amitriptyline has a two-fold effect. Once the active ingredient in the brain occupied different binding sites for messengers and changed so that the influence of these messengers to the brain metabolism. Secondly, amitriptyline transport substances, again carrying back the messengers serotonin and noradrenalin after successful signal transmission in their memory blocks. As a result remain serotonin and noradrenalin longer on the drugs and increases their effectiveness. Amitriptyline solves this way anxiety and voltage States and repeals depressive upsets. The soothing effect of amitriptyline occurs usually very quickly while the mood enhancing adjuvants effect uses only after about two weeks of regular use.

In chronic pain, the pain signals in the brain processing is often disturbed. The neurotransmitter serotonin plays a major role in setting up a filter for incoming pain signals. Through the influence of serotonin, amitriptyline may replace the constant intake of painkillers. The drug must be taken then regularly for pain relief for a long time.

Special features of the effect of amitriptyline beta 10

Notes to the dosage instructions on the packaging and in the patient information:

The medicine contains the active ingredient amitriptyline in the form of amitriptyline hydrochloride. 10 Mg of amitriptyline correspond to 11.32 mg amitriptyline hydrochloride.

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Price comparison

The table below shows all alternatives to amitriptyline 10 beta: it drugs are listed, also offered 10 mg amitriptyline / film-coated tablet as a film-coated tablet with the drug dosage.
(Please note also our notes about the price and payment information)

Price comparison
Sort according to: drug pack size price per film-coated tablets price per box	-Ad-
Drug	Pack size	Price per Film-coated tablet	Cheapest price per Pack (with surcharge),(Versandkosten)
Barcelo Neurin 10	20 Film-coated tablets	0.51 EUR	10.15 EUR
Barcelo Neurin 10	50 Film-coated tablets	0,23 EUR	Price 11,26 EUR (5.00 EUR), (3,95 EUR shipping) price comparison
Barcelo Neurin 10	100 Film-coated tablets	0.13 EUR	Price 12,98 EUR (5.00 EUR), (3,95 EUR shipping) price comparison
Amitriptyline beta 10	20 Film-coated tablets	0.51 EUR	Price 10,29 EUR (5.00 EUR), (3,95 EUR shipping) price comparison
Amitriptyline beta 10	50 Film-coated tablets	0,22 EUR	11.10 EUR (5.00 EUR), price (3,95 EUR shipping) price comparison
Amitriptyline beta 10	100 Film-coated tablets	0.12 EUR	12.32 EUR (5.00 EUR), price (3,95 EUR shipping) price comparison
Novoprotect 10 mg	20 Film-coated tablets	0.51 EUR	10.15 EUR
Novoprotect 10 mg	50 Film-coated tablets	0,22 EUR	11,11 EUR
Novoprotect 10 mg	100 Film-coated tablets	0.12 EUR	12,46 EUR
9 of 9 medications

• All existing medicines containing the same active ingredient as amitriptyline beta 10

Back to the overview

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Warnings & precautions

• The reactivity is affected especially in the first few days of treatment. In this context, also the drive and use machines is severely restricted. Driving of vehicles should be avoided in the first few days of treatment.
• Regular medical blood pressure checks are advisable in patients with high blood pressure and unstable circulatory conditions, because it can cause strong waste of blood pressure during treatment.
• Monitoring of cardiac function and ECG-checks by the physician are recommended in patients with cardiovascular disease.
• Regular medical monitoring of liver enzymes should be done in patients with liver disease.
• A regular medical check of renal function is recommended especially in older patients.
• Regular medical checks of blood count should be made because there may be changes in blood count.
• Medical checks in particular in the event of fever and flu infections are necessary over the entire treatment.
• The regular medical examination of the teeth is important because more and more dental caries was observed in long-term use.
• During the treatment with the drug, medical EEG controls of the brain activity on a regular basis are carried.
• Severely depressed patients and especially young adults under 30 are more suicidal despite therapy until an improvement.
• The sudden discontinuation of long-term high-dose therapy should be avoided because it can cause adverse reactions (agitation, anxiety, sweating, dizziness, vomiting, diarrhea, headache, insomnia) otherwise.
• In the event of a manic (popular upscale) mood or symptoms in the context of a schizophrenic illness the active ingredient is immediately put off.
• At propensity to epilepsy and brain damage may be reinforced by the drug seizures.
• In patients with hyperthyroidism or when administration of thyroid hormones, special medical care be taken as unwanted heart-damaging effects can be amplified.
• The Narkosearzt on the treatment with the drug should be informed before surgery.
• Contact lens providers may incur damage to the cornea due to a reduced activity of the Tränendrüse.
• Intense sunlight should be avoided during treatment with the drug.
• The antidepressant effect of the drug is weakened by nicotine (smoking).
• Alcohol enhances the damping-off effect of the drug and reinforces the deterioration of responsiveness.
• The treatment of children and young people under 18 with the drug is allowed only in exceptional cases.
• The drug can cause an increased risk of bone fractures.
• The drug contains lactose (milk sugar) and is not suitable for patients with glucose utilization disorder.
• In elderly or debilitated patients, in patients with disorders of the brain, respiratory and cardiovascular function and disorders of kidney and liver function, dosage must be adjusted by the doctor.

Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.

Should you perceive signs of an allergic reaction, immediately inform a doctor.

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Interactions

Beta 10 is aware of the interactions of the active substance amitriptyline, amitriptyline? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

Interactions between amitriptyline are especially with active substances which have a also consciousness dampening effect, such as tranquilizers and sedatives. These resources, but also alcohol, there may be a mutual effect enhancement by amitriptyline.

A mutual reinforcement of efficiency is achieved with active substances which have anticholinergic effects such as amitriptyline. These include phenothiazines (a group of psychiatric drugs), Antiparkinsonmittel such as Biperiden, antihistamines (used as a sleep aid and against allergies), or atropine (included for example in eye drops).

Cimetidine (against stomach ulcers) and methylphenidate (for example in hyperactive children used) increase the effects and side effects of the active substance amitriptyline.

Some gefäßverengenden resources (Catecholamines), even if they occur only as an addition to the local anaesthetic means, be strengthened by amitriptyline in their effect on the nervous system.

Special medical caution is required if prior or simultaneously antidepressants of other groups of active ingredients have been taken with amitriptyline or be. This applies in particular for the active ingredients of fluoxetine and fluvoxamine, but also for other tricyclic antidepressants. Here it comes with concurrent administration of amitriptyline to the mutual strengthening of the effect and the increase in the incidence of side-effects. To increase dose of amitriptyline and/or the other antidepressants should be adjusted by your doctor.

Antidepressants from the Group of the MAO-inhibitor allowed due to severe side effects not together with amitriptyline. The revenue must be completed at least 14 days before taking amitriptyline MAO-inhibitors. Even with a reverse switch from amitriptyline to MAO-inhibitors, this minimum distance of 14 days applies.

Antipsychotic drugs, which also affect the mind, strengthen amitriptyline in its effect. This also applies to the concomitant treatment with AEDs such as benzodiazepines or barbiturates. Here, seizures of central nervous system can occur more and more.

Amitriptyline may reduce the action of some drugs against high blood pressure such as, for example, Guanethidine, Reserpine, Betanidin, clonidine, or revoke. The same applies to the active ingredient Alpha-Methyldopa.

Special medical care be taken when simultaneous administration of thyroid hormones as undesirable cardiac adverse effects can be amplified.

Active substances against cardiac arrhythmia of type of the Amiodarone or quinidine are reinforced in their effect by amitriptyline. Active substances that speed up the reduction of amitriptyline in the liver, such as barbiturates, the Epilepsiemittel of carbamazepine and phenytoin, such as nicotine or hormonal contraceptives reduce the effect of amitriptyline. At the same time, carbamazepine and phenytoin are reinforced in their effect by amitriptyline.

With concurrent administration of blood clotting agents of coumarin type such as, for example, Phenprocoumon, there may be changes in blood clotting. The coagulation values must be verified therefore regularly by doctors.

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Dosage

The dosage is patient and the severity of his Erkankung always tailored to the respective tailored. The doctor will choose always the smallest, effective for a patient dose. For non-response of patients to treatment, he will try to go to the limit of the available dosage range.

Outside the hospital a starting dose is recommended for the treatment of depressive disorders by 50 to 75 mg of amitriptyline per day, according to up to six tablets with 10 milligrams of the active substance. The dose should be increased then daily until the effect. However a maximum daily intake must not exceed this 150 milligrams of active ingredient. Daily maximum 300 mg of amitriptyline are allowed in the hospital.

Should young people and children under the age of 16 with amitriptyline be treated (which is allowed only in exceptional cases), amitriptyline is used at a daily level between 25 and 150 milligrams (three to five tablets to 10 milligrams). The maximum dose is amitriptyline at four to five milligrams per kilogram of body weight.

The tablets be taken with liquid, preferably with water, whole. Whether taking to or outside a meal takes place is not important.

If an einschlafen-promoting effect is to be achieved (the doctor decides), a greater proportion of the daily intake can be taken to the night.

The doctor sets the required duration of the medicinal application. Usually, it is at least six months. At the end of the treatment, the dosage of the drug must be reduced again gradually.

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Contra-indications

The following information beta 10 of contra-indications for the purposes of amitriptyline in General, pregnancy & lactation, and children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

When amitriptyline cannot use beta 10?

The active ingredient may not be used for:

• Hypersensitivity to amitriptyline or other antidepressants, Tri and tetrazyklische
• simultaneous use of MAO inhibitors (antidepressants)
• Poisoning by sedatives, painkillers, psychotropic drugs or alcohol
• Patients with a delirium
• untreated narrow-angle glaucoma (green star) (for injection)
• benign prostatic hyperplasia with residual urine formation and/or urinary
• Constriction of Magenausgangs (pyloric stenosis) or krampf-related intestinal obstruction
• Stimulus transfer disturbances to the heart muscle or blockages in the heart-excitation line system with heart beat slow
• Potassium deficiency or simultaneous treatment with medications (for example, drainage products) that cause a lack of potassium.

Amitriptyline may be prescribed only after careful medical risk benefit for:

• benign prostatic hyperplasia without residual urine formation
• severe impairment of liver or kidney function
• Tendency to epileptic seizures
• Errors of Hematopoiesis
• mental disorders due to a brain organic cause
• elderly patients.

In these patient groups need special medical precautions are taken and regular medical checks take place. Manic phases (with extremely fine mood and atmosphere drive) occur in the application of amitriptyline, the active substance must be removed immediately. This applies also, if new experience during treatment, in particular in the course of schizophrenic disorders (schizophrenia), additional depressive symptoms.

What must you consider when pregnancy and breast-feeding?

So far, there is no evidence that amitriptyline could harm the unborn child. As a security precaution, the use in pregnancy, especially in the first three months, however only for compelling reasons, and after careful medical risk benefit should be carried out. Amitriptyline is used towards the end of pregnancy, the newborn must be monitored by doctors during the first months on the after effects of the active substance.

Since amitriptyline passes into breast milk, the active ingredient in the breast-feeding should be used. Where appropriate, must be breast-fed from treatment with amitriptyline previously.

What is taken into account in children?

Children and young people under 18 years of age the active substance should not be taken up, because there are no sufficient experience for this group of patients. If the doctor deems necessary the use of the active substance in younger patients, the application may be only after strict risk benefit and under its control.

Manufacturer: betapharm Arzneimittel GmbH
Active ingredient: Amitriptyline

prescription

Side effects

What side effects can the active ingredient of amitriptyline, amitriptyline beta 10 have? In the following, you learn the most important thing possible, well-known side effects of amitriptyline, amitriptyline beta 10. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).

Very common side effects: dry mouth, stuffy nose, fatigue, drowsiness, sweating, dizziness, low blood pressure, circulatory disorders, heart palpitations, cardiac arrhythmia, irritation, speech, trembling, errors of the insight, headache, constipation, weight gain, liver enzyme increase in value in the blood (usually temporarily).

Common side effects: bladder voiding disorders, restlessness, lack of blood sodium, feeling of thirst, rashes, taste disorders, movement disorders, operated, confusion, overactivity, libido loss, impotence, delirium (especially in older patients).

Uncommon side effects: circulatory collapse, high blood pressure, water retention in tissues (face, tongue), ringing in the ears, intestinal obstruction, diarrhea, Harnsperre, changes in leukocyte (white blood deficiency), abnormal milk, liver dysfunction with bile congestion, fear, paranoia, excitation, arrhythmia, heart muscle weakness of amplification, allergic skin reactions, allergic Gefäßentzündungen, Herzmuskelentzündung.

Rare side effects: hair loss, refusal of eating (anorexia), enlargement of the salivary gland, hypersensitivity to light, delusions, breast enlargement, increase in body temperature.

Very rare side effects: absence of granulocytes, brain seizures, movement disorders in the face, General nerve pains, green star-Anfälle (glaucoma), allergic alveoli inflammation (Alveolitis, Löffler’s syndrome), heart muscle damage, special cardiac arrhythmia (Torsades de pointes).

Specialities: Many of the unwanted side effects are strongest at the beginning of treatment and usually subside when the body to the active substance has accustomed.

Epileptic seizures can occur in special risk groups such as epileptics, alcoholics, or patients taking other drugs.

The active ingredient can cause delirium in older or hirngeschädigten patients. Confusional and other délirante symptoms such as disorientation and delusions are often found, especially in elderly people and patients with Crohn’s Parkinson’s disease or Parkinson’s disease syndromes.

Acute overdose is characterized by Hyperexcitation (up to cramps), consciousness (up to coma), cardiac arrythmias and respiratory failure. If signs of these symptoms, but also increased you in their dry mouth or problems observed during urination and increased pulse, this indicates an incipient overdose. Then immediately talk to your doctor.

Treatment with amitriptyline should not abruptly be stopped because this can cause side effects such as nausea, insomnia and anxiety. It is advisable to reduce (to sneak out) the dose slowly.

In children, an increased risk for tooth decay (dental caries) is due to the treatment. It must be so particular attention paid to the daily dental care.

The widespread use of the active substance showed that taking can lead to an increased risk of bone fractures.